Dr. Liu Jinsong, PhD

Position: Dean of the School & Hospital of Stomatology, Wenzhou Medical University

Email: jinsong0719@wmu.edu.cn

Phone: +86-13587969097

Biography

Dr. Jinsong Liu is the Dean of the School & Hospital of Stomatology at Wenzhou Medical University. His research primarily focuses on nanotechnology for dental implants, bio-inspired functionally aided tissue engineering, and enabling technologies for bone regeneration. Dr. Liu holds a Bachelor's, Master's, and Ph.D. in Stomatology, all from Sichuan University. He has worked as a dentist at Dazhou Central Hospital and at the School & Hospital of Stomatology, Wenzhou Medical University, where he served as Vice Dean and is now the Dean. Dr. Liu is an active member of the Chinese Stomatology Society and the Chinese Society for Biomaterials. His work has been recognized by multiple research grants and prestigious awards.

Research Interests

· Nanotechnology for dental implants

· Bio-inspired functionally aided tissue engineering

· Enabling technologies for bone regeneration

Education

· Bachelor of Stomatology, Sichuan University (1998-2001)

· Master’s Degree in Stomatology, Sichuan University (2002-2005)

· Ph.D. in Stomatology, Sichuan University (2007-2010)

Work Experience

· 1995-2001: Dentist, Dazhou Central Hospital, Dazhou, China

· 2005-2016: Dentist, School & Hospital of Stomatology, Wenzhou Medical University, Wenzhou, China

· 2016-2024: Vice Dean, School & Hospital of Stomatology, Wenzhou Medical University

· 2024-Present: Dean, School & Hospital of Stomatology, Wenzhou Medical University

Memberships

· Chinese Stomatology Society

· Chinese Society for Biomaterials

Grants

· National Natural Science Foundation of China (2013-2017)

· National Natural Science Foundation of China (2018-2022)

· National Natural Science Foundation of China (2021-2024)

· National Natural Science Foundation of China (2024-2027)

Selected Publications

1. Al-Baadani, M.A., Xu, L., Cai, K., Yie, K.H.R., Shen, Y., Al-Bishari, A.M., Al-Shaaobi, B.A., Ma, P., Shen, X., Liu, J. "Preparation of co-electrospinning membrane loaded with simvastatin and substance P to accelerate bone regeneration by promoting cell homing, angiogenesis and osteogenesis." Materials Today Bio, 21 (2023).

2. Al-Baadani, M.A., Xu, L., Yie, K.H.R., Sun, A., Gao, X., Cai, K., Al-Shaaobi, B.A., Al-Bishari, A.M., Cai, L., Shen, X., Liu, J., Ma, P. "In situ preparation of alendronate-loaded ZIF-8 nanoparticles on electrospun nanofibers for accelerating early osteogenesis in osteoporosis." Materials & Design, 217 (2022).

3. Al-Baadani, M.A., Yie, K.H.R., Al-Bishari, A.M., Al-Shaaobi, B.A., Zhou, Z., Fang, K., Dai, B., Shen, Y., Ma, J., Liu, J., Shen, X. "Co-electrospinning polycaprolactone/gelatin membrane as a tunable drug delivery system for bone tissue regeneration." Materials & Design, 209 (2021).

4. Al-Bishari, A.M., Liu, T., Zhuang, J., Zhang, Q., Chen, J., Wang, Y., Liu, C., Gao, P., Liu, J., Lu, L. "Triple-layered multi-functional membrane for synergistic enhancement of guided bone regeneration." Materials & Design, 239 (2024).

5. Al-Bishari, A.M., Yie, K.H.R., Al-Baadani, M.A., Al-Shaaobi, B.A., Zhou, Z., Fang, K., Sun, A., Shen, Y., Cai, L., Yao, L., Ding, X., Shen, X., Liu, J. "JK-2 loaded electrospun membrane for promoting bone regeneration." Materials Science and Engineering C-Materials for Biological Applications, 130 (2021).

6. Bi, W., Liu, Y., Guo, J., Lin, Z., Liu, J., Zhou, M., Wismeijer, D., Pathak, J.L., Wu, G. "All-trans retinoic-acid inhibits heterodimeric bone morphogenetic protein 2/7-stimulated osteoclastogenesis, and resorption activity." Cell and Bioscience, 8 (2018).

7. Deng, Z., Huang, Z., Ping, L., Hu, W., Yie, K.H.R., Liu, C., Zhang, H., Liu, J. "The combined treatment of fiber post and root canal by the Er:YAG laser enhances the bond strength of composite reconstruction." Lasers in Medical Science, 38(1) (2023).

8. Deng, Z., Wang, L., Zhang, D., Liu, J., Liu, C., Ma, J. "Lanthanum-containing hydroxyapatite coating on ultrafine-grained titanium by micro-arc oxidation: A promising strategy to enhance overall performance of titanium." Medical Science Monitor, 20 (2014).

9. Deng, Z., Yin, B., Li, W., Liu, J., Yang, J., Zheng, T., Zhang, D., Yu, H., Liu, X., Ma, J. "Surface characteristics of and in vitro behavior of osteoblast-like cells on titanium with nanotopography prepared by high-energy shot peening." International Journal of Nanomedicine, 9 (2014) 5565-5573.

10. Ding, X., Wang, Y., Xu, L., Zhang, H., Deng, Z., Cai, L., Wu, Z., Yao, L., Wu, X., Liu, J., Shen, X. "Stability and osteogenic potential evaluation of micro-patterned titania mesoporous-nanotube structures." International Journal of Nanomedicine, 14 (2019) 4133-4144.

11. Dong, Y., Yao, L., Cai, M., Forouzanfar, T., Wu, L., Liu, J., Wu, G. "Antimicrobial and Pro-Osteogenic Coaxially Electrospun Magnesium Oxide Nanoparticles-Polycaprolactone /Parathyroid Hormone-Polycaprolactone Composite Barrier Membrane for Guided Bone Regeneration." International Journal of Nanomedicine, 18 (2023) 369-383.

12. Dong, Y., Ye, H., Liu, Y., Xu, L., Wu, Z., Hu, X., Ma, J., Pathak, J.L., Liu, J., Wu, G. "pH dependent silver nanoparticles releasing titanium implant: A novel therapeutic approach to control peri-implant infection." Colloids and Surfaces B-Biointerfaces, 158 (2017) 127-136.

13. Fang, K., Shen, Y., Yie, K.H.R., Zhou, Z., Cai, L., Wu, S., Al-Bishari, A.M., Al-Baadani, M.A., Shen, X., Ma, P., Liu, J. "Preparation of Zirconium Hydrogen Phosphate Coatings on Sandblasted/Acid-Etched Titanium for Enhancing Its Osteoinductivity and Friction/Corrosion Resistance." International Journal of Nanomedicine, 16 (2021) 8265-8277.

14. Gao, P., Zhang, Q., Sun, Y., Cheng, H., Wu, S., Zhang, Y., Si, W., Sun, H., Sun, N., Yang, J., Cai, K., Lu, L., Liu, J. "Synergistic catecholamine and coordination chemistry for enhanced bioactivity and secondary grafting activity of zirconia dental implants." Colloids and Surfaces B-Biointerfaces, 246 (2025).

15. Gao, X., Al-Baadani, M.A., Wu, M., Tong, N., Shen, X., Ding, X., Liu, J. "Study on the Local Anti-Osteoporosis Effect of Polaprezinc-Loaded Antioxidant Electrospun Membrane." International Journal of Nanomedicine, 17 (2022) 17-29.

16. W. Hu, K.H.R. Yie, C. Liu, J. Zhu, Z. Huang, B. Zhu, D. Zheng, B. Yang, B. Huang, L. Yao, J. Liu, X. Shen, Z. Deng, Improving the valence self-reversible conversion of cerium nanoparticles on titanium implants by lanthanum doping to enhance ROS elimination and osteogenesis, Dental Materials 38(8) (2022) 1362-1375.

17. Y. Jin, L. Xu, X. Hu, S. Liao, J.L. Pathak, J. Liu, Lithium chloride enhances bone regeneration and implant osseointegration in osteoporotic conditions, Journal of Bone and Mineral Metabolism 35(5) (2017) 497-503.

18. S. Liao, H. Deng, S. Huang, J. Yang, S. Wang, B. Yin, T. Zheng, D. Zhang, J. Liu, G. Gao, J. Ma, Z. Deng, Design, synthesis and evaluation of novel 5,6,7-trimethoxyflavone-6-chlorotacrine hybrids as potential multifunctional agents for the treatment of Alzheimer's disease, Bioorganic & Medicinal Chemistry Letters 25(7) (2015) 1541-1545.

19. C. Liu, Z. Huang, J. Zhu, X. Liu, B. Zhu, D. Zheng, B. Yang, R. Tao, C. Cai, X. Chen, J. Liu, Z. Deng, Near-ultraviolet irradiation to stimulate unmodified polyether ether ketone to achieve stable and sustainable antibacterial activity, Colloids and Surfaces B-Biointerfaces 229 (2023).

20. J. Liu, J.L. Pathak, X. Hu, Y. Jin, Z. Wu, M.A. Al-Baadani, S. Wu, H. Zhang, S. Farkasdi, Y. Liu, J. Ma, G. Wu, Sustained Release of Zoledronic Acid from Mesoporous TiO₂-Layered Implant Enhances Implant Osseointegration in Osteoporotic Condition, Journal of Biomedical Nanotechnology 14(11) (2018) 1965-1978.

21. J. Liu, Z. Wu, H. He, K. Cai, H. Zhang, L. Xu, Gallium and silicon synergistically promote osseointegration of dental implant in patients with osteoporosis, Medical Hypotheses 103 (2017) 35-38.

22. J. Liu, Y. Zeng, S. Shi, L. Xu, H. Zhang, J.L. Pathak, Y. Pan, Design of polyaspartic acid peptide-poly (ethylene glycol)-poly (ε-caprolactone) nanoparticles as a carrier of hydrophobic drugs targeting cancer metastasized to bone, International Journal of Nanomedicine 12 (2017) 3561-3575.

23. J. Liu, H. Zhang, Y. Dong, Y. Jin, X. Hu, K. Cai, J. Ma, G. Wu, Bi-directionally selective bone targeting delivery for anabolic and antiresorptive drugs: A novel combined therapy for osteoporosis?, Medical Hypotheses 83(6) (2014) 694-696.

24. Y. Liu, X. Ma, J. Guo, Z. Lin, M. Zhou, W. Bi, J. Liu, J. Wang, H. Lu, G. Wu, All-trans retinoic acid can antagonize osteoblastogenesis induced by different BMPs irrespective of their dimerization types and dose-efficiencies, Drug Design Development and Therapy 12 (2018) 3419-3430.

25. W. Lou, Y. Dong, H. Zhang, Y. Jin, X. Hu, J. Ma, J. Liu, G. Wu, Preparation and Characterization of Lanthanum-Incorporated Hydroxyapatite Coatings on Titanium Substrates, International Journal of Molecular Sciences 16(9) (2015) 21070-21086.

26. P. Ma, Y. Yu, K.H.R. Yie, K. Fang, Z. Zhou, X. Pan, Z. Deng, X. Shen, J. Liu, Effects of titanium with different micro/nano structures on the ability of osteoblasts to resist oxidative stress, Materials Science & Engineering C-Materials for Biological Applications 123 (2021).

27. X. Shen, M.A. Al-Baadani, H. He, L. Cai, Z. Wu, L. Yao, X. Wu, S. Wu, M. Chen, H. Zhang, J. Liu, Antibacterial and osteogenesis performances of LL37-loaded titania nanopores in vitro and in vivo, International Journal of Nanomedicine 14 (2019) 3043-3054.

28. X. Shen, K. Fang, K.H.R. Yie, Z. Zhou, Y. Shen, S. Wu, Y. Zhu, Z. Deng, P. Ma, J. Ma, J. Liu, High proportion strontium-doped micro-arc oxidation coatings enhance early osseointegration of titanium in osteoporosis by anti-oxidative stress pathway, Bioactive Materials 10 (2022) 405-419.

29. X. Shen, L. Ping, L. Wang, C. Liu, J. Liu, Z. Deng, Improving the stability and bioactivity of micro-arc oxidized calcium phosphate/titania porous coatings by high energy shot peening pretreatment, Ceramics International 46(2) (2020) 2041-2048.

30. X. Shen, K.H.R. Yie, X. Wu, Z. Zhou, A. Sun, A.M. Al-bishari, K. Fang, M.A. Al-Baadani, Z. Deng, P. Ma, J. Liu, Improvement of aqueous stability and anti-osteoporosis properties of Zn-MOF coatings on titanium implants by hydrophobic raloxifene, Chemical Engineering Journal 430 (2022).