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Biomedical Engineering

Xiance Jin

Dr. Xiance Jin, PhD

Position:

· Vice Dean of School of Basic Medical Science of Wenzhou Medical University

· Chief Medical Physicist and Director of Radiotherapy Center, Department of Radiotherapy, The First Affiliated Hospital of Wenzhou Medical University

Institution:

· The First Affiliated Hospital of Wenzhou Medical University

Education Background:

· 2007.08 - 2011.08: Ph.D. in Medical Physics, University of Toledo

o Major: Medical Physics

o Advisor: Dr. E. Ishmael Parsai

o Thesis: Evaluation of Large Area Polycrystalline CdTe Detector for Diagnostic X-ray Imaging

· 1997.09 - 2001.07: B.Sc. in Physics, Zhejiang University (China)

Professional Experience:

· 2021.4 - Present: Vice Dean of School of Basic Medical Science of Wenzhou Medical University, Chief Medical Physicist and Director of Radiotherapy Center, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China

· 2021.1 - 2021.4: Chief Medical Physicist and Director of Radiotherapy Center, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China

· 2011.08 - 2020.1: Radiotherapy Physicist and Vice Director of Department of Radiation and Medical Oncology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China

· 2001.08 - 2007.08: Radiotherapy Physicist, Radiation Oncology Department, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China

Expert Key Words:

· Radiation Physics

· IMRT

· VMAT

· Artificial Intelligence

· Radiomics

Committee Services:

· Chair, Education and Training Committee of Asia-Oceania Federation of Medical Physics (AFOMP)

· Council Member of IOMP and Professional Relationship Committee Member of International Organization for Medical Physics (IOMP)

· Board Member and Committee Member for the International Medical Physics Certification Board (IMPCB, 2013-2020)

· Education and Training Committee of IOMP

· Professional Relationship Committee Member of IOMP (2014-2020)

· Associate Editor, Journal of Applied Clinical Medical Physics (JACMP)

· Associate Editor, Technology in Cancer Research & Treatment

· Subcommittee Member of International Library Subcommittee and Member of Exchange Scientist Program Subcommittee of AAPM

· Vice Chair, Radiotherapy Physics Group of Radiation Oncology Committee of Chinese Medical Association

· Member of Standing Committee of Chinese Society of Medical Physics

· Chairman, Zhejiang Anticancer Association of Radiation Physics Technology Group (AARPTG)

· Committee Member of Radiotherapy Technology Branch of Chinese Association of Medical Equipment

· Committee Member of Medical Physics Branch of Chinese Society of Biomedical Engineering

· Vice Chairman and General Secretary of Younger Committee of Medical Physics Branch of Chinese Society of Biomedical Engineering

· Vice Chairman of Radiation Oncology Branch Wujieping Medical Foundation

· Member of Youth Commission of Zhejiang Anticancer Association

· Committee Member and General Secretary of Radiotherapy and Chemotherapy

· Committee of Wenzhou Medical Association

Patents

1. Xiance Jin, Juebin Jin, Yao Ai. Fast feature extraction, Rapid diagnosis and Disease course Prediction system based on Radiology for COVID-19. China Invention patent, CN202011391447.8

2. Xiance Jin, Yao Ai, Juebin Jin. A prediction model and device for tumor diagnosis and treatment based on artificial intelligence. China Invention patent, CN202010400098.5

3. Xiance Jin, Congying Xie. A precision dose verification device for cancer patients. China Invention patent, ZL201911001895.x

4. Xiance Jin, Congyng Xie, Yongqiang Zhou. Multi-center volumetric modulated arc radiotherapy dose verification phantom and method for ultra-long target area. China Invention patent, 201710764870.X

5. Xiance Jin, Congying Xie, Meixiao Shen. A precise control method of radiotherapy instrument for adaptive radiotherapy of eye tumor. China Invention patent. ZL201711200237.4

6. Xiance Jin, Congying Xie, Meixiao Shen, Real time localization system based on eye ball movement for intraocular cancer. China Invention patent, ZL201410856051.4

7. Congying Xie, Xiance Jin, Vision fixation device for ocular tumor radiotherapy. China National New Style Functional Patent, Serial Number: ZL 201220270789.9

8. Shixiu Wu, Xiance Jin, Computed radiography portal imaging system. China National New Style Functional Patent, Serial Number: ZL 200420078686.6

Awards

1. Technical Innovation of early diagnosis of Thoracic tumor and Construction of accurate treatment system

Congying Xie, Xiance Jin, Men Hou, Huafang Su, Ji Zhang, Lei Zhuang, Hanbin Chen, Didi Chen, Lanxiao Shen,

China Zhejiang Province Science and Technology Award, 2021, Third Prize

2. Precise radiotherapy and clinical effects on thoracic cancer

Congying Xie, Xiance Jin, Huafang Su, Xueban Zhang, Shengliu Xue, Lanxiao Shen, Ya fang, Jinling Yi, Zhiqing Wu

China Zhejiang Province Science and Technology Award, 2017, Third Prize

3. SIB-IMRT in the treatment of NPC and parotid function protection

Congying Xie, Xiance Jin, Huafang Su, Shengliu Xue, Xia Deng, Jinling Yi

China Zhejiang Province Innovation Award on Health and Medicine, 2013, Third Prize

China Zhejiang Province Science and Technology Award, 2013, Third Prize

China Wenzhou Science and Technology Advancement Award 2013, Third Prize

4. “Series Study of IMRT in the treatment Nasopharyngeal Carcinoma”

Shixiu Wu, Congying Xie, Xiance Jin, Aizhong Chen, Jianghua Wang, Ping Zhang, Jiangyi Yu, and Lizhang

China National Science and Technology Award on Medicine 2007, Third Prize

China Zhejiang Province Innovation Award on Health and Medicine, 2007, First Prize

China Zhejiang Province Science and Technology Award2007, Third Prize,

China Wenzhou Science and Technology Advancement Award 2007, Second Prize,

Research funding

1. National Natural Science Foundation of China, 12475352, Study on individualized dose prediction method for radiotherapy of esophageal cancer based on deep learning of CT images, 2025/01-2028/12,0.52M RMB, Role: principle investigator

2. Key Project of Natural Science Foundation of Zhejiang Province,Z24A050009,Individualized radiotherapy dose study of esophageal cancer guided by deep learning CT imaging features,2024/01-2026/12,0.3 M RMB, Role: principle investigator

3. 2024 National Health Commission Scientific Research Fund - Key project of Zhejiang Provincial Health Major Science and Technology Plan,WKJ-ZJ-2437,Research and development of key technologies of individualized diagnosis and treatment decision system for brain metastases based on multimodal imaging,2024/01-2026/12,0.15 M RMB, Role: principle investigator

4. Major Science and Technology Projects of Wenzhou Municipal Science and Technology Bureau, ZY2022016, Research and Development of synchronous radiotherapy and chemotherapy decision system for esophageal Cancer based on Medical big data and Radiomics, 2023.1.1-2025.12.30, 0.3 M RMB; Role: Principle investigate

5. Major Science and Technology Projects of Wenzhou Municipal Science and Technology Bureau, 2018ZY016, Precise radiation therapy on intraocular cancer, 2019/1/1-2021//12/31,0.7 M RMB; Role: Principle investigate,

6. National Natural Science Foundation of China, 11675122, OCT guided adaptive radiotherapy for ocular cancer, 2017/01-2020/12,0.52M RMB, Role: principle investigator

7. Natural funding of Zhejiang Province, LY16H160046: OCT guided adaptive radiotherapy for ocular cancer, Role: principle investigator

8. Funding from Wenzhou Municipal Science and Technology Bureau, Y20140709, Non-invasive localization system for ocular cancer based on OCT, Role: principle investigator

9. Medical and health science and technology project from Department of Health of Zhejiang Province, 2015115273,Image guided precise radiotherapy for ocular cancer based on OCT. Role: principle investigator

10. Funding from Zhejiang Human Resources and Social Security Bureau, 604090656/037,treatment plan quality index for plan evaluation and comparison, Role: principle investigator

11. Funding from Wenzhou Municipal Science and Technology Bureau, Y20120137, Planning quality index for simultaneous integrated boost IMRT in the treatment of nasopharyngeal cancer patients. Role: principle investigator

12. National Natural Science Foundation of China, 81602658, The mechanism of miR-1275 in regulating the acquired epithelial-mesenchymal transition (EMT) and radioresistance of esophageal cancer, 2017/01-2019/12, 0.17 M RMB, Role: Major investigator (3rd )

Book

1. Xiance Jin, Congying Xie Shenxiang Yan. Handbook of organs movement and management in radiotherapy. Science Press. CIP 253022, 2023.6

2. Xiance Jin, Congying Xie. Quality control manual for Radiation Oncology Physics. Science Press. CIP 034471, 2018.6

3. AFOMP GUIDELINES ON RADIATION ONCOLOGY OPERATION DURING COVID-19.2020.4

4. “Chapter 8. Medical Physics during the COVID-19 Pandemic: Global Perspectives – Asia Pacific” Xiance Jin, Fu Jin, Hasin Anupama Azhari, Woo Sang Ahn. Cheryl Lian Pei Ling, Congying Xie. Hui Yu Tsai In book: Medical Physics During the COVID-19 Pandemic Global Perspectives in Clinical Practice, Education and Research Edited By Kwan Hoong Ng, Magdalena S. Stoeva. ISBN 9780367693756, March 25, 2021, by CRC Press

Published Papers

1. Xie C, Yu X, Tan N, Zhang J, Su W, Ni W, Li C, Zhao Z, Xiang Z, Shao L, Li H, Wu J, Cao Z, Jin J, Jin X. Combined deep learning and radiomics in pretreatment radiation esophagitis prediction for patients with esophageal cancer underwent volumetric modulated arc therapy. Radiother Oncol. 2024 Jul 14:110438.

2. Su W, Cheng D, Ni W, Ai Y, Yu X, Tan N, Wu J, Fu W, Li C, Xie C, Shen M, Jin X. Multi-omics Deep Learning for Radiation Pneumonitis Prediction in Lung Cancer Patients underwent Volumetric Modulated Arc Therapy. Computer Methods and Programs in Biomedicine. 2024 Jun 19;254:108295.

3. Li C, Zhang J, Ning B, Xu J, Lin Z, Zhang J, Tan N, Yu X, Su W, Ni W, Yu W, Wu J, Cao G, Cao Z, Xie C, Jin X. Radiation pneumonitis prediction with dual-radiomics for esophageal cancer underwent radiotherapy. Radiat Oncol,2024, 19:72.

4. Ai Y, Zhu X, Zhang Y, Li W, Li H, Zhao Z, Zhang J, Ning B, Li C, Zheng Q, Zhang J, Jin J, Li Y, Xie C, Jin X. MRI radiomics nomogram integrating postoperative adjuvant treatments in recurrence risk prediction for patients with early-stage cervical cancer. Radiother Oncol. 2024 May 16:110328.

5. Shen Y, Tang X, Lin S, Jin X, Ding J, Shao M. Automatic dose prediction using deep learning and plan optimization with finite-element control for intensity modulated radiation therapy. Med Phys. Med Phys. 2024 Jan;51(1):545-555.

6. Lei X, Cao Z, Wu Y, Lin J, Zhang Z, Jin J, Ai Y, Zhang J, Du D, Tian Z, Xie C, Yin W, Jin X. Preoperative prediction of clinical and pathological stages for patients with esophageal cancer using PET/CT radiomics. Insights Imaging. 2023 Oct 15;14(1):174.

7. Shen Y, Tang X, Lin S, Jin X, Ding J, Shao M. Automatic dose prediction using deep learning and plan optimization with finite-element control for intensity modulated radiation therapy. Med Phys. 2023 Sep 25. doi: 10.1002/mp.16743

8. Han C, Zhang J, Yu B, Zheng H, Wu Y, Lin Z, Ning B, Yi J, Xie C, Jin X. Integrating plan complexity and dosiomics features with deep learning in patient-specific quality assurance for volumetric modulated arc therapy. Radiat Oncol. 2023 Jul 11;18(1):116. (Ⅱ)

9. Zheng H, Zheng Q, Jiang M, Chen D, Han C, Yi J, Ai Y, Yan J, Jin X. Evaluation the benefits of additional radiotherapy for gastric cancer patients after D2 resection using CT based radiomics. Radiol Med. 2023 May 15. 10.1007/s11547-023-01646-1. (Ⅱ)

10. Zhang Z, Wan X, Lei X, Wu Y, Zhang J, Ai Y, Yu B, Liu X, Jin J, Xie C, Jin X. Intra- and peri-tumoral MRI radiomics features for preoperative lymph node metastasis prediction in early-stage cervical cancer. Insights into Imaging. Insights Imaging. 2023 Apr 15;14(1):65. (Ⅱ)

Abstracts

1. Xiance Jin, Intelligent treatment decision system for cervical cancer based on ultrasound radiomics, Invited keynote speaker, AOCMP, 2022 Taipei, Taiwan, December 10-12, 2022

2. Xiance Jin, Preparing Medical Physicists for challenging situations. IUPESM WC2022. Word congress on medical physics and biomedical engineering, Sands Expos and convention center, Singapore, 12-17 June 2022

3. Xiance Jin, Clinical practice of VMAT and QA studies. the AMPICON2021, Bengaluru, India, the 42nd National Conference of the Association of Medical Physicists of India from 19th-21st May 2022.

4. Xiance Jin, Clinical practice of VMAT and QA studies. the AMPICON2021, Bengaluru, India, the 42nd National Conference of the Association of Medical Physicists of India from 19th-21st May 2022.

5. Xiance Jin, Ultrasound images based radiomics. Conference on radiation in health care (CRHC 2021) International medical physics week. Department of radiological physics SMS Medical College and Hospitals, Jaipur, India. 26-27 April 2021.

6. Xiance Jin, Medical physics during Covid 19. The 121st Scientific Meeting of the Japan Society of Medical Physics(JSMP), April 15th -18, 2021, in Yokohama, Japan.

7. Xiance Jin, Ultrasound images based radiomics for Early Prediction and Protection of Cervical Cancer. Annual Conference of Bangladesh Medical Physics Society. Friday 18 December 2020.

8. Xiance Jin, Yao Ai, Congying Xie, Noninvasive prediction of lymph node status for patients with early-Stage cervical cancer based on radiomics features from ultrasound images. Engineering and Physical Sciences in Medicine Conference and Asia-Oceania Congress of Medical Physics 2019, Oct 27th -30th 2019; Perth, Australia, Oral presentation.

9. Xiance Jin, Ji Zhang, Congying Xie, Pathological differentiation of primary lung cancer with contrast enhanced CT radiomics of brain metastases, Engineering and Physical Sciences in Medicine Conference and Asia-Oceania Congress of Medical Physics 2019, Oct 27th -30th 2019; Perth, Australia, Oral presentation.

10. Xiance Jin, Xiaomin Zheng, Congying Xie, Integrated treatment response prediction model combining radiomic features and dosimetric parameters for esophageal cancer patients underwent chemoradiation using machine learning. SANTRO 10-year anniversary scientific session, October 21-24, San Antonio, Texas, Oral presentation, Best Abstract Award for Younger Investigator.

Contact Information:

· Email: jinxc1979@hotmail.com

· Phone: 86-15957704166

· Fax: 0086-55578999-664166

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